ZELTIQ(R) Aesthetics Reaches 2,000,000th CoolSculpting(R) Treatment Cycle Milestone

ZELTIQ(R) Aesthetics Reaches 2,000,000th CoolSculpting(R) Treatment Cycle Milestone

CoolSculpting Procedure Continues to Grow Noninvasive Fat Reduction Market

PLEASANTON, CA– (Marketwired) –05/14/15–ZELTIQAesthetics, Inc.(NASDAQ: ZLTQ), a medical technology company focused on developing and commercializing products utilizing its proprietary controlled-cooling technology platform, today announced it recently shipped its 2,000,000thCoolSculpting treatment cycle.

“As demonstrated by the shipment of our 2,000,000thcycle, the physician and consumer communities have embraced CoolSculpting as a procedure that works and that continues to expand the overall aesthetic market since non-invasive fat reduction appeals to a much broader range of the population, including men,” saidMark Foley, President and Chief Executive Officer ofZELTIQ. “We estimate that, on average, a patient receives approximately 4 cycles per treatment which would imply that we have treated roughly 500,000 patients to date. While the shipment of our 2,000,000thcycle is an incredible accomplishment for the company, our market research shows that 22 million people in US alone are interested in reducing fat noninvasively1, which would suggest that we are still in the early stages of creating and growing the non-invasive fat reduction market. Again, we are very excited about this significant achievement in the history of the Company.”

The one and only CoolSculpting procedure was developed by Harvard scientists and is based on the proprietary science of Cryolipolysis, a process demonstrating that when fat cells are exposed to extreme cold, they die and are eliminated naturally from the body. Fat cells treated and eliminated by the procedure are gone for good, and patients can expect long-lasting results. There are over 3,500 CoolSculpting systems placed in nearly 3,000 practices in over 70 countries around the world. Furthermore, 25% of North American CoolSculpting centers have more than one Coolsculpting system in the practice.

About the CoolSculptingProcedure
The CoolSculpting procedure is a non-surgical, clinically proven procedure that selectively reduces fat bulges in problem areas using a patented cooling technology. Cleared by theFDAfor noninvasive fat reduction in the abdomen, flank and thighs, it gently cools unwanted fat cells in the body to induce a natural, controlled elimination of fat cells without harming surrounding tissue, and the treated fat cells are gone for good. CoolSculpting treatments have been performed in over 70 countries around the world. The CoolSculpting procedure is available through an elite network of CoolSculpting Centers worldwide. Dermatologists, plastic surgeons and leading aesthetic specialists that offer the CoolSculpting procedure can be found atwww.coolsculpting.com. Be sure to follow the CoolSculpting procedure onFacebook,Twitter,PinterestandYouTube.

AboutZELTIQAesthetics, Inc.
ZELTIQ Aesthetics, Inc.is a medical technology company focused on developing and commercializing products utilizing its proprietary controlled-cooling technology platform.ZELTIQ’sfirst commercial product, the CoolSculptingsystem, is designed to selectively reduce stubborn fat that may not respond to diet or exercise. The CoolSculpting procedure is based on the scientific principle that fat cells are more sensitive to cold than the overlying skin and surrounding tissues. It utilizes patented technology of precisely controlled cooling to reduce the temperature of fat cells in the treated area, which is intended to cause fat cell elimination through a natural biological process known as apoptosis.ZELTIQdeveloped the CoolSculpting procedure to safely, noticeably, and measurably reduce the fat layer.

1Data on file.

Source:ZELTIQ Aesthetics, Inc.

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